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Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism

Blind mole rats Spalax (BMR) are small subterranean rodents common in the Middle East. BMR is distinguished by its adaptations to life underground, remarkable longevity (with a maximum documented lifespan of 21 y), and resistance to cancer. Spontaneous tumors have never been observed in spalacids. T...

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Bibliografiska uppgifter
Huvudupphovsmän: Gorbunova, Vera, Hine, Christopher, Tian, Xiao, Ablaeva, Julia, Gudkov, Andrei V., Nevo, Eviatar, Seluanov, Andrei
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511137/
https://ncbi.nlm.nih.gov/pubmed/23129611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217211109
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