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Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication

BACKGROUND: Cancer cell responses to chemotherapeutic agents vary, and this may reflect different defects in DNA repair, cell-cycle checkpoints, and apoptosis control. Cytometry analysis only quantifies dye-incorporation to examine DNA content and does not reflect the biological complexity of the ce...

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Bibliografski detalji
Glavni autori: Sakaue-Sawano, Asako, Kobayashi, Tamiyo, Ohtawa, Kenji, Miyawaki, Atsushi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277280/
https://ncbi.nlm.nih.gov/pubmed/21226962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-12-2
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