Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication

BACKGROUND: Cancer cell responses to chemotherapeutic agents vary, and this may reflect different defects in DNA repair, cell-cycle checkpoints, and apoptosis control. Cytometry analysis only quantifies dye-incorporation to examine DNA content and does not reflect the biological complexity of the ce...

Full description

Saved in:
Bibliographic Details
Main Authors: Sakaue-Sawano, Asako, Kobayashi, Tamiyo, Ohtawa, Kenji, Miyawaki, Atsushi
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277280/
https://ncbi.nlm.nih.gov/pubmed/21226962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-12-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items