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Receptor Activator of NF-κB Ligand (RANKL) Protects Against Hepatic Ischemia/Reperfusion Injury in Mice

The transcription factor NF-κB plays diverse roles in the acute injury response to hepatic ischemia/reperfusion (I/R). Activation of NF-κB in Kupffer cells promotes inflammation through cytokine expression while activation in hepatocytes may be cell protective. The interaction of receptor activator...

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Detalhes bibliográficos
Main Authors: Sakai, Nozomu, Van Sweringen, Heather L., Schuster, Rebecca, Blanchard, John, Burns, Justin M., Tevar, Amit D., Edwards, Michael J., Lentsch, Alex B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276725/
https://ncbi.nlm.nih.gov/pubmed/22031462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24756
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