The peptidyl-prolyl isomerase, Pin1, facilitates NF-κB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury

BACKGROUND/AIMS: Our previous work suggested an important role for the peptidyl-prolyl isomerase, Pin1, in hepatic NF-κB activation and liver injury during ischemia/reperfusion (I/R). In this study, we sought to determine the function of Pin1 in the injury response to hepatic I/R. METHODS: Wild-type...

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Bibliografski detalji
Glavni autori: Kuboki, Satoshi, Sakai, Nozomu, Clarke, Callisia, Schuster, Rebecca, Blanchard, John, Edwards, Michael J., Lentsch, Alex B.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747648/
https://ncbi.nlm.nih.gov/pubmed/19515451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.04.016
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