Age-Related Decrease in Proteasome Expression Contributes to Defective NF-κB Activation during Hepatic Ischemia/Reperfusion

Hepatic ischemia/reperfusion (I/R) leads to liver injury and dysfunction through the initiation of a biphasic inflammatory response that is regulated by the transcription factor, NF-κB. We have previously shown that there is an age-dependent difference in the injury response to hepatic I/R in mice t...

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Autores principales: Huber, Nadine, Sakai, Nozomu, Eismann, Thorsten, Shin, Thomas, Kuboki, Satoshi, Blanchard, John, Schuster, Rebecca, Edwards, Michael J., Wong, Hector R., Lentsch, Alex B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695826/
https://ncbi.nlm.nih.gov/pubmed/19206148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22840
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