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DNA Methylation Signatures in Development and Aging of the Human Prefrontal Cortex
The human prefrontal cortex (PFC), a mastermind of the brain, is one of the last brain regions to mature. To investigate the role of epigenetics in the development of PFC, we examined DNA methylation in ∼14,500 genes at ∼27,000 CpG loci focused on 5′ promoter regions in 108 subjects range in age fro...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276664/ https://ncbi.nlm.nih.gov/pubmed/22305529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.12.020 |
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