Kava Components Down-Regulate Expression of AR and AR Splice Variants and Reduce Growth in Patient-Derived Prostate Cancer Xenografts in Mice

Men living in Fiji and drinking kava have low incidence of prostate cancer (PCa). However, the PCa incidence among Fijian men who had migrated to Australia, increased by 5.1-fold. We therefore examined the potential effects of kava root extracts and its active components (kavalactones and flavokawai...

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Detalhes bibliográficos
Main Authors: Li, Xuesen, Liu, Zhongbo, Xu, Xia, Blair, Christopher A., Sun, Zheng, Xie, Jun, Lilly, Michael B., Zi, Xiaolin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276576/
https://ncbi.nlm.nih.gov/pubmed/22347450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031213
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