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Dietary feeding of flavokawain A, a Kava chalcone, exhibits a satisfactory safety profile and its association with enhancement of phase II enzymes in mice

Flavokawain A (FKA), a major chalcone in the Kava plant, has recently demonstrated promising anti-cancer activities. A systematic evaluation of FKA's safety profile has not been reported before. In this study, male FVB/N mice were fed with an AIN-76A diet or AIN-76A diet supplemented with 0.6%...

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Bibliographic Details
Published in:Toxicol Rep
Main Authors: Li, Xuesen, Xu, Xia, Ji, Tao, Liu, Zhongbo, Gu, Mai, Hoang, Bang H., Zi, Xiaolin
Format: Artigo
Language:Inglês
Published: Elsevier 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219529/
https://ncbi.nlm.nih.gov/pubmed/25379458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.02.002
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