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Flavokawain B, a kava chalcone, exhibits robust apoptotic mechanisms on androgen receptor-negative, hormone-refractory prostate cancer cell lines and reduces tumor growth in a preclinical model

Limited success has been achieved in extending the survival of patients with metastatic and hormone-refractory prostate cancer (HRPC). There is a strong need for novel agents in the treatment and prevention of HRPC. We have shown that flavokawain B (FKB), a kava chalcone, is about 4 to 12 fold more...

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Detalles Bibliográficos
Autores principales: Tang, Yaxiong, Li, Xuesen, Liu, Zhongbo, Simoneau, Anne R., Xie, Jun, Zi, Xiaolin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888737/
https://ncbi.nlm.nih.gov/pubmed/20112340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25210
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