Analysis of miRNA and mRNA Expression Profiles Highlights Alterations in Ionizing Radiation Response of Human Lymphocytes under Modeled Microgravity

BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR pathway can originate from alteration in the functionality of the microRNA-mediated gene regulation, being...

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Detalhes bibliográficos
Main Authors: Girardi, Cristina, De Pittà, Cristiano, Casara, Silvia, Sales, Gabriele, Lanfranchi, Gerolamo, Celotti, Lucia, Mognato, Maddalena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276573/
https://ncbi.nlm.nih.gov/pubmed/22347458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031293
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