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The B-Cell Specific Transcription Factor, Oct-2, Promotes Epstein-Barr Virus Latency by Inhibiting the Viral Immediate-Early Protein, BZLF1

The Epstein-Barr virus (EBV) latent-lytic switch is mediated by the BZLF1 immediate-early protein. EBV is normally latent in memory B cells, but cellular factors which promote viral latency specifically in B cells have not been identified. In this report, we demonstrate that the B-cell specific tran...

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Detalhes bibliográficos
Main Authors: Robinson, Amanda R., Kwek, Swee Sen, Kenney, Shannon C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276558/
https://ncbi.nlm.nih.gov/pubmed/22346751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002516
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