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The B-Cell-Specific Transcription Factor and Master Regulator Pax5 Promotes Epstein-Barr Virus Latency by Negatively Regulating the Viral Immediate Early Protein BZLF1

The latent-to-lytic switch of Epstein-Barr virus (EBV) is mediated by the immediate early protein BZLF1 (Z). However, the cellular factors regulating this process remain incompletely characterized. In this report, we show that the B-cell-specific transcription factor Pax5 helps to promote viral late...

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Detalhes bibliográficos
Main Authors: Raver, Ryan M., Panfil, Amanda R., Hagemeier, Stacy R., Kenney, Shannon C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700198/
https://ncbi.nlm.nih.gov/pubmed/23678172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00546-13
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