Methylation-Dependent Binding of the Epstein-Barr Virus BZLF1 Protein to Viral Promoters

The switch between latent and lytic Epstein-Barr virus (EBV) infection is mediated by the viral immediate-early (IE) protein, BZLF1 (Z). Z, a homologue of c-jun that binds to AP1-like motifs (ZREs), induces expression of the BRLF1 (R) and BRRF1 (Na) viral proteins, which cooperatively activate trans...

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Detalhes bibliográficos
Main Authors: Dickerson, Sarah J., Xing, Yongna, Robinson, Amanda R., Seaman, William T., Gruffat, Henri, Kenney, Shannon C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654727/
https://ncbi.nlm.nih.gov/pubmed/19325883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000356
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