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A Genomewide Screen for Suppressors of Alu-Mediated Rearrangements Reveals a Role for PIF1
Alu-mediated rearrangement of tumor suppressor genes occurs frequently during carcinogenesis. In breast cancer, this mechanism contributes to loss of the wild-type BRCA1 allele in inherited disease and to loss of heterozygosity in sporadic cancer. To identify genes required for suppression of Alu-me...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276492/ https://ncbi.nlm.nih.gov/pubmed/22347400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030748 |
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