DBC2, a candidate for a tumor suppressor gene involved in breast cancer

A previously uncharacterized gene, DBC2 (deleted in breast cancer), was cloned from a homozygously deleted region at human chromosome 8p21. DBC2 contains a highly conserved RAS domain and two putative protein interacting domains. Our analyses indicate that DBC2 is the best candidate tumor suppressor...

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Autors principals: Hamaguchi, Masaaki, Meth, Jennifer L., von Klitzing, Christine, Wei, Wen, Esposito, Diane, Rodgers, Linda, Walsh, Tom, Welcsh, Piri, King, Mary-Claire, Wigler, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC129730/
https://ncbi.nlm.nih.gov/pubmed/12370419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212516099
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