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Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits
A tumor suppressor gene, Adenomatous polyposis coli (Apc), is expressed in the nervous system from embryonic to adulthood stages, and transmits the Wnt signaling pathway in which schizophrenia susceptibility genes, including T-cell factor 4 (TCF4) and calcineurin (CN), are involved. However, the fun...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276361/ https://ncbi.nlm.nih.gov/pubmed/22347851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2011.00085 |
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