Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice

BACKGROUND: Neuronal nitric oxide synthase (nNOS) is involved in the regulation of a diverse population of intracellular messenger systems in the brain. In humans, abnormal NOS/nitric oxide metabolism is suggested to contribute to the pathogenesis and pathophysiology of some neuropsychiatric disorde...

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Autors principals: Tanda, Koichi, Nishi, Akinori, Matsuo, Naoki, Nakanishi, Kazuo, Yamasaki, Nobuyuki, Sugimoto, Tohru, Toyama, Keiko, Takao, Keizo, Miyakawa, Tsuyoshi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711944/
https://ncbi.nlm.nih.gov/pubmed/19538708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-19
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