Loading...

Replication Stress-Induced Chromosome Breakage Is Correlated with Replication Fork Progression and Is Preceded by Single-Stranded DNA Formation

Chromosome breakage as a result of replication stress has been hypothesized to be the direct consequence of defective replication fork progression, or “collapsed” replication forks. However, direct and genome-wide evidence that collapsed replication forks give rise to chromosome breakage is still la...

Full description

Saved in:
Bibliographic Details
Main Authors: Feng, Wenyi, Di Rienzi, Sara C., Raghuraman, M. K., Brewer, Bonita J.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276152/
https://ncbi.nlm.nih.gov/pubmed/22384343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.111.000554
Tags: Add Tag
No Tags, Be the first to tag this record!