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Propofol Neurotoxicity Is Mediated by p75 Neurotrophin Receptor Activation

BACKGROUND: Propofol exposure to neurons during synaptogenesis results in apoptosis leading to cognitive dysfunction in adulthood. Previous work from our laboratory showed that isoflurane neurotoxicity occurs through p75 neurotrophin receptor (p75(NTR)) and subsequent cytoskeleton depolymerization....

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Detaylı Bibliyografya
Asıl Yazarlar: Pearn, Matthew L., Hu, Yue, Niesman, Ingrid R., Patel, Hemal H., Drummond, John C., Roth, David M., Akassoglou, Katerina, Patel, Piyush M., Head, Brian P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275822/
https://ncbi.nlm.nih.gov/pubmed/22198221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318242a48c
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