Propofol Neurotoxicity Is Mediated by p75 Neurotrophin Receptor Activation

BACKGROUND: Propofol exposure to neurons during synaptogenesis results in apoptosis leading to cognitive dysfunction in adulthood. Previous work from our laboratory showed that isoflurane neurotoxicity occurs through p75 neurotrophin receptor (p75(NTR)) and subsequent cytoskeleton depolymerization....

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Detalhes bibliográficos
Main Authors: Pearn, Matthew L., Hu, Yue, Niesman, Ingrid R., Patel, Hemal H., Drummond, John C., Roth, David M., Akassoglou, Katerina, Patel, Piyush M., Head, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275822/
https://ncbi.nlm.nih.gov/pubmed/22198221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318242a48c
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