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Asymmetric Synthesis of Dihydroindanes by Convergent Alkoxide-Directed Metallacycle-Mediated Bond Formation

A convergent synthesis of highly substituted and stereodefined dihydroindanes is described from alkoxide-directed Ti-mediated cross-coupling of internal alkynes with substituted 4-hydroxy-1,6-enynes (substrates that derive from 2-directional functionalization of readily available epoxy alcohol deriv...

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Main Authors: Greszler, Stephen N., Reichard, Holly A., Micalizio, Glenn C.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275653/
https://ncbi.nlm.nih.gov/pubmed/22235773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2105043
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