Tolerance and Withdrawal From Prolonged Opioid Use in Critically Ill Children

OBJECTIVE: After prolonged opioid exposure, children develop opioid-induced hyperalgesia, tolerance, and withdrawal. Strategies for prevention and management should be based on the mechanisms of opioid tolerance and withdrawal. PATIENTS AND METHODS: Relevant manuscripts published in the English lang...

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Autores principales: Anand, Kanwaljeet J. S., Willson, Douglas F., Berger, John, Harrison, Rick, Meert, Kathleen L., Zimmerman, Jerry, Carcillo, Joseph, Newth, Christopher J. L., Prodhan, Parthak, Dean, J. Michael, Nicholson, Carol
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275643/
https://ncbi.nlm.nih.gov/pubmed/20403936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1542/peds.2009-0489
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