IS “RESCUE” THERAPY ETHICAL IN RANDOMIZED CONTROLLED TRIALS?

OBJECTIVE: There is a commonly held belief that randomized, placebo-controlled trials in pediatric critical care should incorporate “rescue” therapy (open-label administration of active drug) when a child’s condition is deteriorating. The ethical, conceptual and analytic challenges related to “rescu...

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Detalhes bibliográficos
Main Authors: Holubkov, Richard, Michael Dean, J., Berger, John, Anand, K. J. S., Carcillo, Joseph, Meert, Kathleen, Zimmerman, Jerry, Newth, Christopher, Harrison, Rick, Willson, Douglas F., Nicholson, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259684/
https://ncbi.nlm.nih.gov/pubmed/19307815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0b013e318198bd13
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