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A single nucleotide polymorphism in the corticotropin receptor gene is associated with a blunted cortisol response during pediatric critical illness

OBJECTIVE: The cortisol response during critical illness varies widely among patients. Our objective was to examine single nucleotide polymorphisms (SNPs) in candidate genes regulating cortisol synthesis, metabolism, and activity to determine if genetic differences were associated with variability i...

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Bibliografische gegevens
Gepubliceerd in:Pediatr Crit Care Med
Hoofdauteurs: Jardine, David, Emond, Mary, Meert, Kathleen L., Harrison, Rick, Carcillo, Joseph A., Anand, Kanwaljeet J. S., Berger, John, Newth, Christopher J. L., Willson, Douglas F., Nicholson, Carol, Dean, J. Michael, Zimmerman, Jerry J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712687/
https://ncbi.nlm.nih.gov/pubmed/25055195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0000000000000193
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