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Partners in crime: the TGFβ and MAPK pathways in cancer progression

The TGFβ and Ras-MAPK pathways play critical roles in cell development and cell cycle regulation, as well as in tumor formation and metastasis. In the absence of cellular transformation, these pathways operate in opposition to one another, where TGFβ maintains an undifferentiated cell state and supp...

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Detalhes bibliográficos
Main Authors: Chapnick, Douglas A, Warner, Lisa, Bernet, Jennifer, Rao, Timsi, Liu, Xuedong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275500/
https://ncbi.nlm.nih.gov/pubmed/22204556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-1-42
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