Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export

The NS1 protein of influenza virus is a major virulence factor essential for virus replication, as it redirects the host cell to promote viral protein expression. NS1 inhibits cellular messenger ribonucleic acid (mRNA) processing and export, down-regulating host gene expression and enhancing viral g...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Zhang, Liang, Das, Priyabrata, Schmolke, Mirco, Manicassamy, Balaji, Wang, Yaming, Deng, Xiaoyi, Cai, Ling, Tu, Benjamin P., Forst, Christian V., Roth, Michael G., Levy, David E., García-Sastre, Adolfo, de Brabander, Jef, Phillips, Margaret A., Fontoura, Beatriz M.A.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275370/
https://ncbi.nlm.nih.gov/pubmed/22312003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107058
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items