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Altered synaptic marker abundance in the hippocampal stratum oriens of Ts65Dn mice is associated with exuberant expression of versican

DS (Down syndrome), resulting from trisomy of chromosome 21, is the most common cause of genetic mental retardation; however, the molecular mechanisms underlying the cognitive deficits are poorly understood. Growing data indicate that changes in abundance or type of CSPGs (chondroitin sulfate proteo...

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Autori principali: Howell, Matthew D, Gottschall, Paul E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Neurochemistry 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275338/
https://ncbi.nlm.nih.gov/pubmed/22225533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110037
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