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Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome

Down syndrome (DS) is the most common genetic cause of intellectual disability, and arises from trisomy of human chromosome 21. Accumulating evidence from studies of both DS patient tissue and mouse models has suggested that synaptic dysfunction is a key factor in the disorder. The presence of sever...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Marland, Jamie R. K., Smillie, Karen J., Cousin, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726538/
https://ncbi.nlm.nih.gov/pubmed/26808141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147974
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