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Binding Modes of μ-Conotoxin to the Bacterial Sodium Channel (Na(V)Ab)

Polypeptide toxins isolated from the venom of cone snails, known as μ-conotoxins, block voltage-gated sodium channels by physically occluding the ion-conducting pathway. Using molecular dynamics, we show that one subtype of μ-conotoxins, PIIIA, effectively blocks the bacterial voltage-gated sodium c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chen, Rong, Chung, Shin-Ho
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Biophysical Society 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274799/
https://ncbi.nlm.nih.gov/pubmed/22325270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.041
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