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Mechanism of μ-Conotoxin PIIIA Binding to the Voltage-Gated Na(+) Channel Na(V)1.4
Several subtypes of voltage-gated Na(+) (Na(V)) channels are important targets for pain management. μ-Conotoxins isolated from venoms of cone snails are potent and specific blockers of different Na(V) channel isoforms. The inhibitory effect of μ-conotoxins on Na(V) channels has been examined extensi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968119/ https://ncbi.nlm.nih.gov/pubmed/24676211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093267 |
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