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Cytoskeleton Disruption in J774 Macrophages: Consequences for Lipid Droplet Formation and Cholesterol Flux

Macrophages store excess unesterified cholesterol (free, FC) in the form of cholesteryl ester (CE) in cytoplasmic lipid droplets. The hydrolysis of droplet-CE in peripheral foam cells is critical to HDL-promoted reverse cholesterol transport because it represents the first step in cellular cholester...

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Detalhes bibliográficos
Main Authors: Weibel, Ginny L., Joshi, Michelle R., Jerome, W. Gray, Bates, Sandra R., Yu, Kevin J., Phillips, Michael C., Rothblat, George H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274585/
https://ncbi.nlm.nih.gov/pubmed/22015387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2011.09.015
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