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15(S)-Lipoxygenase-1 associates with neutral lipid droplets in macrophage foam cells: evidence of lipid droplet metabolism

15(S)-lipoxygenase-1 (15-LO-1) was present in the whole-cell homogenate of an acute human monocytic leukemia cell line (THP-1). Additionally, 15-LO-1 was detected on neutral lipid droplets isolated from THP-1 foam cells. To investigate if 15-LO-1 is active on lipid droplets, we used the mouse leukem...

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Detalhes bibliográficos
Main Authors: Weibel, Ginny L., Joshi, Michelle R., Wei, Cong, Bates, Sandra R., Blair, Ian A., Rothblat, George H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781309/
https://ncbi.nlm.nih.gov/pubmed/19528634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900081-JLR200
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