Structure and expression of a cloned beta o thalassaemic globin gene.

We have cloned the single beta-globin gene from an Italian patient who is a double heterozygote for beta o/delta beta o thalassaemia. RNA isolated from nucleated red cells from this patient can be translated in vitro to give detectable levels of A gamma- G gamma and alpha-globin, but no beta-globin....

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Bibliographic Details
Main Authors: Moschonas, N, de Boer, E, Grosveld, F G, Dahl, H H, Wright, S, Shewmaker, C K, Flavell, R A
Format: Artigo
Language:Inglês
Published: 1981
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC327442/
https://ncbi.nlm.nih.gov/pubmed/6272205
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