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Structure and expression of a cloned beta o thalassaemic globin gene.

We have cloned the single beta-globin gene from an Italian patient who is a double heterozygote for beta o/delta beta o thalassaemia. RNA isolated from nucleated red cells from this patient can be translated in vitro to give detectable levels of A gamma- G gamma and alpha-globin, but no beta-globin....

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Udgivet i:Nucleic Acids Res
Principais autores: Moschonas, N, de Boer, E, Grosveld, F G, Dahl, H H, Wright, S, Shewmaker, C K, Flavell, R A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6272205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.17.4391
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