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SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton
Noonan syndrome is one of the most common causes of human congenital heart disease and is frequently associated with missense mutations in the protein phosphatase SHP-2. Interestingly, patients with acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL), juvenile myelomonocytic leukemi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Company of Biologists
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3274356/ https://ncbi.nlm.nih.gov/pubmed/22278918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.067579 |
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