IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling

In primary neurons, the oncofetal RNA-binding protein IGF2BP1 (IGF2 mRNA-binding protein 1) controls spatially restricted β-actin (ACTB) mRNA translation and modulates growth cone guidance. In cultured tumor-derived cells, IGF2BP1 was shown to regulate the formation of lamellipodia and invadopodia....

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Autors principals: Stöhr, Nadine, Köhn, Marcel, Lederer, Marcell, Glaß, Markus, Reinke, Claudia, Singer, Robert H., Hüttelmaier, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273841/
https://ncbi.nlm.nih.gov/pubmed/22279049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.177642.111
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