Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

The RNA-binding protein IGF2BP1 (IGF-II mRNA binding protein 1) stabilizes the c-myc RNA by associating with the Coding Region instability Determinant (CRD). If and how other proteins cooperate with IGF2BP1 in promoting stabilization of the c-myc mRNA via the CRD remained elusive. Here, we identify...

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Autors principals: Weidensdorfer, Doreen, Stöhr, Nadine, Baude, Anne, Lederer, Marcell, Köhn, Marcel, Schierhorn, Angelika, Buchmeier, Sabine, Wahle, Elmar, Hüttelmaier, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612774/
https://ncbi.nlm.nih.gov/pubmed/19029303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1175909
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