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Illuminating the reaction pathway of the FokI restriction endonuclease by fluorescence resonance energy transfer

The FokI restriction endonuclease is a monomeric protein that recognizes an asymmetric sequence and cleaves both DNA strands at fixed loci downstream of the site. Its single active site is positioned initially near the recognition sequence, distant from its downstream target 13 nucleotides away. Mor...

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Detalhes bibliográficos
Main Authors: Pernstich, Christian, Halford, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273807/
https://ncbi.nlm.nih.gov/pubmed/21993298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr809
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