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Transient cleavage kinetics of the Eco RI restriction endonuclease measured in a pulsed quench-flow apparatus: enzyme concentration-dependent activity change.

We report measurements of the cleavage rate of pBR 322 plasmid DNA by the restriction endonuclease Eco RI as a function of enzyme and DNA concentration. The reaction, which at high excess of enzyme over DNA occurs between 0.2 and 5 seconds, was studied by the means of a microprocessor controlled pul...

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Autors principals: Langowski, J, Urbanke, C, Pingoud, A, Maass, G
Format: Artigo
Idioma:Inglês
Publicat: 1981
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC327365/
https://ncbi.nlm.nih.gov/pubmed/6269084
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