The effect of several nucleic acid binding drugs on the cleavage of d(GGAATTCC) and pBR 322 by the Eco RI restriction endonuclease.

The endonucleolytic action of the EcoRI restriction enzyme on the double-stranded oligonucleotide d(GGAATTCC) and the supercoiled plasmid DNA pBR 233 is inhibited by actinomycin D, ethidium bromide, proflavin, distamycin A and netropsin. Half-maximal inhibition is observed at around 100 microM conce...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Goppelt, M, Langowski, J, Pingoud, A, Haupt, W, Urbanke, C, Mayer, H, Maass, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1981
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327588/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.22.6115
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