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Dispersal evolution in neoplasms: The role of disregulated metabolism in the evolution of cell motility

Here we apply the theoretical framework of dispersal evolution to understand the emergence of invasive and metastatic cells. We investigate whether the disregulated metabolism characteristic of cancer cells may play a causal role in selection for cell motility, and thus to the tissue invasion and me...

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Autori principali: Aktipis, C. Athena, Maley, Carlo C., Pepper, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273626/
https://ncbi.nlm.nih.gov/pubmed/21930797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0004
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