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Life history tradeoffs in cancer evolution

Somatic evolution during cancer progression and therapy results in tumor cells that exhibit a wide range of phenotypes including rapid proliferation and quiescence. Evolutionary life history theory may help us understand the diversity of these phenotypes. Fast life history organisms reproduce rapidl...

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Autori principali: Aktipis, C. Athena, Boddy, Amy M., Gatenby, Robert A., Brown, Joel S., Maley, Carlo C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010142/
https://ncbi.nlm.nih.gov/pubmed/24213474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3606
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