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Murine regulatory T cells contain hyper-proliferative and death-prone subsets with differential ICOS expression
Regulatory T cells (Treg) are crucial for self-tolerance. It has been an enigma that Treg exhibit an anergic phenotype reflected by hypo-proliferation in vitro following T cell receptor (TCR) stimulation but undergo vigorous proliferation in vivo. We report here that, different from conventional T c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273604/ https://ncbi.nlm.nih.gov/pubmed/22231701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102448 |
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