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Murine regulatory T cells contain hyper-proliferative and death-prone subsets with differential ICOS expression

Regulatory T cells (Treg) are crucial for self-tolerance. It has been an enigma that Treg exhibit an anergic phenotype reflected by hypo-proliferation in vitro following T cell receptor (TCR) stimulation but undergo vigorous proliferation in vivo. We report here that, different from conventional T c...

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Sonraí Bibleagrafaíochta
Main Authors: Chen, Yong, Shen, Shudan, Gorentla, Balachandra, Gao, Jimin, Zhong, Xiao-Ping
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273604/
https://ncbi.nlm.nih.gov/pubmed/22231701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102448
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