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Pleiotropic patterning response to activation of Shh signaling in the limb Apical Ectodermal Ridge

Sonic hedgehog (Shh) signaling in the limb plays a central role in coordination of limb patterning and outgrowth. Shh expression in the limb is limited to the cells of the Zone of Polarizing Activity (ZPA), located in posterior limb bud mesoderm. Shh is not expressed by limb ectoderm or AER, but rec...

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書誌詳細
主要な著者: Wang, Chi-Kuang Leo, Tsugane, Mizuyo H., Scranton, Victoria, Kosher, Robert A., Pierro, Louis J., Upholt, William B., Dealy, Caroline N.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273424/
https://ncbi.nlm.nih.gov/pubmed/21465622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22628
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