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Pleiotropic patterning response to activation of Shh signaling in the limb Apical Ectodermal Ridge

Sonic hedgehog (Shh) signaling in the limb plays a central role in coordination of limb patterning and outgrowth. Shh expression in the limb is limited to the cells of the Zone of Polarizing Activity (ZPA), located in posterior limb bud mesoderm. Shh is not expressed by limb ectoderm or AER, but rec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Chi-Kuang Leo, Tsugane, Mizuyo H., Scranton, Victoria, Kosher, Robert A., Pierro, Louis J., Upholt, William B., Dealy, Caroline N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273424/
https://ncbi.nlm.nih.gov/pubmed/21465622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22628
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