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The apical ectodermal ridge is a timer for generating distal limb progenitors
The apical ectodermal ridge (AER) is a transient embryonic structure essential for the induction, patterning and outgrowth of the vertebrate limb. However, the mechanism of AER function in limb skeletal patterning has remained unclear. In this study, we genetically ablated the AER by conditionally r...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574509/ https://ncbi.nlm.nih.gov/pubmed/18359901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.018945 |
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