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The apical ectodermal ridge is a timer for generating distal limb progenitors

The apical ectodermal ridge (AER) is a transient embryonic structure essential for the induction, patterning and outgrowth of the vertebrate limb. However, the mechanism of AER function in limb skeletal patterning has remained unclear. In this study, we genetically ablated the AER by conditionally r...

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Detalhes bibliográficos
Main Authors: Lu, Pengfei, Yu, Ying, Perdue, Yasmine, Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574509/
https://ncbi.nlm.nih.gov/pubmed/18359901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.018945
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