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Pleiotropic patterning response to activation of Shh signaling in the limb Apical Ectodermal Ridge
Sonic hedgehog (Shh) signaling in the limb plays a central role in coordination of limb patterning and outgrowth. Shh expression in the limb is limited to the cells of the Zone of Polarizing Activity (ZPA), located in posterior limb bud mesoderm. Shh is not expressed by limb ectoderm or AER, but rec...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273424/ https://ncbi.nlm.nih.gov/pubmed/21465622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22628 |
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