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TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

The organization and dynamics of receptors and other molecules in the plasma membrane are not well understood. Here we analyzed the spatio-temporal dynamics of T cell antigen receptor (TCR) complexes and linker for activation of T cells (Lat), a key adaptor molecule in the TCR signaling pathway, in...

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Detalhes bibliográficos
Main Authors: Lillemeier, Björn F, Mörtelmaier, Manuel A, Forstner, Martin B, Huppa, Johannes B, Groves, Jay T, Davis, Mark M
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273422/
https://ncbi.nlm.nih.gov/pubmed/20010844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1832
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