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Endocytosis and intracellular trafficking contribute to necrotic neurodegeneration in C. elegans

Unlike apoptosis, necrotic cell death is characterized by marked loss of plasma membrane integrity. Leakage of cytoplasmic material to the extracellular space contributes to cell demise, and is the cause of acute inflammatory responses, which typically accompany necrosis. The mechanisms underlying p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Troulinaki, Kostoula, Tavernarakis, Nektarios
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273398/
https://ncbi.nlm.nih.gov/pubmed/22157748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.447
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