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Endocytosis and intracellular trafficking contribute to necrotic neurodegeneration in C. elegans

Unlike apoptosis, necrotic cell death is characterized by marked loss of plasma membrane integrity. Leakage of cytoplasmic material to the extracellular space contributes to cell demise, and is the cause of acute inflammatory responses, which typically accompany necrosis. The mechanisms underlying p...

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Detalhes bibliográficos
Main Authors: Troulinaki, Kostoula, Tavernarakis, Nektarios
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273398/
https://ncbi.nlm.nih.gov/pubmed/22157748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.447
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