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Identification of mutant firefly luciferases that efficiently utilize aminoluciferins
Firefly luciferase-catalyzed light emission from D-luciferin is widely used as a reporter of gene expression and enzymatic activity both in vitro and in vivo. Despite the power of bioluminescence for imaging and drug discovery, light emission from firefly luciferase is fundamentally limited by the p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273327/ https://ncbi.nlm.nih.gov/pubmed/22195567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.09.019 |
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